The current mandate of the LHC experiments is to precisely determine the properties of the Higgs boson, one of the major interests being the top-Yukawa coupling measurement. The Run 2 data has provided evidence of ttH production at the LHC which is sensitive to the magnitude of the coupling at tree level. In contrast, the single top associated production of the Higgs boson (tH) is uniquely sensitive to the relative sign of the top-Yukawa coupling with respect to the Higgs to vector boson coupling. According to the Standard Model (SM), the cross section of tH process is very low even at 13 TeV centre of mass energy. However, in case of anomalous Higgs couplings the cross section may be enhanced and be detected with limited amount of luminosity. Results are presented from Run 2 measurements of the tH process in multilepton final state using LHC data collected by the CMS experiment. A combination with other Higgs decay modes produces more stringent constraints on beyond SM scenarios compared to Run 1 analysis. Future prospects of the search is discussed in the context of High Luminosity LHC (HL-LHC).