Date Feb 3, 2025, 12:30 pm – 1:30 pm Location Jadwin Hall Audience Physics/Biophysics faculty, post docs, grad students Share on X Share on Facebook Share on LinkedIn Speaker Edo Kussell Affiliation New York University Details Event Description Molecular mechanisms that control cell growth and division enable bacteria and other microorganisms to maintain a narrow range of cell sizes within a population. While the control of cell size is ubiquitous in biology, the evolutionary benefit of maintaining a characteristic cell size is not understood in detail. In this talk, I will analyze the advantage of cell size control strategies in growing populations of bacteria. I will discuss how mortality can select for accurate cell size control, and derive an analytical expression for the optimal cell size. I will show that non-genetic heritability of cell size gives bacteria an evolutionary advantage by enabling selection to act on the distribution of cell sizes in a population to reduce mortality rates. These results will be discussed in the context of experimental measurements in bacteria and their implications for the evolution of size control mechanisms.