Events Archive

Biophysics Seminar: Mustafa Mir, CHOP| Quantifying transcriptional regulation across multiple-scales in developing embryos
Mon, Nov 28, 2022, 12:30 pm1:30 pm
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Free and open to the public
Biophysics Seminar: Tian-Ming Fu, Princeton University| Probing Biological Dynamics in Multicellular Organisms: from long-term electrophysiology to high-resolution imaging
Mon, Nov 21, 2022, 12:30 pm1:30 pm

The urgency to probe biological dynamics is impeded by a major challenge: the large dynamic range of biological processes—interactions of molecules within milliseconds can lead to changes across the whole-organism over days to years. It calls for measurements with both high spatiotemporal resolution and large-scale long-term coverage. However,…

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A free lecture open to the public.
Biophysics Seminar: Anders Hansen, MIT| Dynamics of 3D Genome Structure and Function
Mon, Nov 14, 2022, 12:30 pm1:30 pm

Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop extruding cohesins. These loops and domains are thought to play critical roles in regulating gene expression by regulating long-range enhancer-promoter interactions. But whether CTCF/cohesin loops are stable or dynamic structures was…

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Free and open to the public
Biophysics Seminar: Kandice Tanner, NIH| Microenvironment regulation of metastasis
Mon, Nov 7, 2022, 12:30 pm1:30 pm

In the event of metastatic disease, emergence of a lesion can occur at varying intervals from diagnosis and in some cases following successful treatment of the primary tumor.  Genetic factors that drive metastatic progression have been identified, such as those involved in cell adhesion, signaling, extravasation and metabolism. However,…

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A free lecture open to the public.
Canceled: Biophysics Seminar: Roseanna Zia, Stanford University| How Colloidal Physics Instantiate Life in Biological Cells
Mon, Oct 31, 2022, 12:30 pm1:30 pm

We are interested in how physics at the colloidal scale instantiate life in biological cells. While principles from physics have driven recent paradigm shifts in how collective biomolecular behaviors orchestrate life, many mechanistic aspects of e.g. transcription, translation, and condensation remain mysterious because…

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A free lecture open to the public.
Biophysics Seminar: Marc Gershow, NYU| Maggots! Making Memories and Reading Minds
Mon, Oct 10, 2022, 12:30 pm1:30 pm

My lab studies the brains of larval fruit flies as models of neural computation. We are interested in the rules by which the larval brain transforms sensory input into motor output to navigate an uncertain environment, how the larva’s brain changes these rules as it learns new information, and how these rules and changes are encoded in the…

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Free and open to the public
Biophysics Seminar: Stephen Floor, UCSF| On measurement in RNA biology
Mon, Sep 26, 2022, 12:30 pm1:30 pm

Measurement of natural systems typically involves perturbation and interpretation. In this talk, I will discuss the implications of measurement in the context of RNA in gene expression in human cells. I will focus on measurements of RNA biology using high-throughput sequencing, which are powerful for their scale but also involve perturbations…

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A free lecture open to the public.
Biophysics Seminar: Shenshen Wang, UCLA| Limit and potential of immune learning against changing targets
Mon, Sep 19, 2022, 12:30 pm1:30 pm
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Free and open to the public
Biophysics seminar: Marc Gershow, New York University| TBD
Mon, May 2, 2022, 12:30 pm12:30 pm
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A free lecture open to the public.
Biophysics Seminar: Arseny Finkelstein, Tel-Aviv University| TBA
Sun, May 1, 2022, 12:30 pm1:30 pm
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Free and open to the public
Biophysics seminar: Andrea Liu, University of Pennsylvania| How Materials Can Learn
Mon, Apr 25, 2022, 12:30 pm12:30 pm

How does learning occur? Neural networks learn via optimization, where a loss function is minimized by a computer to achieve the desired result. But physical networks such as mechanical spring networks or flow networks have no central processor so they cannot minimize such a loss function. An alternative is to encode local rules into those…

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A free lecture open to the public.
Biophysics seminar: David Wolpert, Santa Fe Institute| Stochastic Thermodynamics of Distributed Systems
Mon, Apr 18, 2022, 12:30 pm12:30 pm

The new field of stochastic thermodynamics allows us to analyze the thermodynamic behavior of dynamic systems arbitrarily far from thermal equilibrium, and has produced many powerful theorems concerning phenomena completely absent in traditional statistical physics. However, to date stochastic thermodynamics has (mostly) been applied to systems…

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A free lecture open to the public.
Biophysics Seminar: Gijsje Koenderink, Delft University of Technology|Cytoskeletal crosstalk in cell shape and mechanics|Zoom
Mon, Apr 11, 2022, 12:30 pm12:30 pm

Mechanical stability and shape changes of cells are determined by the dynamic interplay of four distinct cytoskeletal networks, made of actin filaments, microtubules, intermediate filaments and septins. These four filamentous systems contribute different structural and dynamical properties, enabling specific cellular…

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A free lecture open to the public.
Biophysics seminar: Sarah L. Keller, University of Washington| Phase-separating membranes of hungry yeast are tiny, living thermostats
Mon, Apr 4, 2022, 12:30 pm12:30 pm

Liquid-liquid phase separation of cell membranes exemplifies a biological system leveraging a physical concept to achieve a chemical end. Here, we show that yeast actively tune the transition temperature of their vacuole membranes to be close to the yeast's growth temperature, which implies that the membrane's proximity to the miscibility…

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A free lecture open to the public.
Biophysics Seminar: Arnold Mathijssen, University of Pennsylvania|Transport and delivery by active droplets and artificial microtubules
Mon, Mar 28, 2022, 12:30 pm12:30 pm

Understanding the physics of living systems allows us to design new materials that are active and adaptive, akin to cells and tissues. Conversely, these active matter systems can reveal fundamental principles in physics and biology. In this talk, I will discuss three systems that feature this synergy, ranging from the molecular to the…

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A free lecture open to the public.
Canceled and will be re-scheduled. Biophysics Seminar: Na Ji| UC Berkeley| Imaging the brain at high spatiotemporal resolution
Mon, Mar 21, 2022, 12:30 pm12:30 pm

To understand computation in the brain, one needs to understand the input-output relationships for neural circuits and the anatomical and functional properties of individual neurons therein. Optical microscopy has emerged as an ideal tool in this quest, as it is capable of recording the activity of neurons distributed over millimeter dimensions…

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A free lecture open to the public.
Biophysics Seminar: Madhav Mani, Northwestern University| A Statistical (Physics) view of Organismal Development
Mon, Feb 28, 2022, 12:30 pm12:30 pm

After a century of biochemical and genetic onslaught on the embryo we are left with an inexhaustive parts list with an increasingly baroque logic. How do we begin to assemble complex living systems from knowledge of the parts list? In this talk I will attempt to pursue a statistical (physics) approach to discerning the design principles that…

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A free lecture open to the public.
Virtual Biophysics Seminar: Zvonimir Dogic, UCSB, Brandeis|Sculpting liquid interfaces with active stresses
Mon, Feb 7, 2022, 12:30 pm12:30 pm

Controlling interfacial structure and dynamics of phase separating fluid mixtures is key to creating diverse functional materials. Traditionally, this is accomplished by controlling interface chemistry, through the presence of surface-modifying amphiphilic agents. Using a phase separating mixture of active and passive fluids, we study how…

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A free lecture open to the public.
Biophysics Seminar: Chris Wiggins, Columbia University|TBD|Zoom
Mon, Dec 13, 2021, 1:15 pm1:15 pm
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A free lecture open to the public.
Biophysics Seminar: Chris Wiggins, Columbia University| Just do the best you can: statistical physics approaches to reinforcement learning
Mon, Dec 13, 2021, 1:15 pm1:15 pm

The most celebrated corners of machine learning over the past decades are those successful at predicting - e.g., spam classification, medical diagnoses, or cat faces. But machine learning as actually used in practice is commonly prescriptive rather than predictive: decisions must be made in order to maximize a reward. The…

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A free lecture open to the public.