Events Archive

Biophysics Seminar: Walter Reisner | McGill University | Nanofluidic Devices for Single-Molecule Analysis, Manipulation and Control
Mon, Sep 25, 2023, 12:30 pm1:30 pm

Nanofluidic devices, e.g. based on nanochannels or nanopores, are networks of fluid-filled structures on a chip with dimensions ~1-100 nm.  These dimensions are on order of molecular length scales, giving rise to the ability to directly analyze, manipulate and confine single biomolecules.  In this talk I will focus on two different…

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Biophysics Seminar: Arup Chakraborty | MIT | The Evolution of Antibody Responses upon Vaccination
Mon, Sep 18, 2023, 12:30 pm1:30 pm

Infectious disease-causing pathogens have plagued humanity since antiquity, and the COVID-19 pandemic has been a vivid reminder of this perpetual existential threat. Vaccination has saved more lives than any other medical procedure, and effective vaccines have helped control the COVID-19 pandemic. However, we do not have effective vaccines…

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Biophysics Seminar: Bill Bialek & Josh Shaevitz | Princeton University | State of the Center
Mon, Sep 11, 2023, 12:30 pm1:30 pm
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Biophysics Seminar: José Alvarado, University of Texas Austin| Connecting active “hardware” to biological “software”
Mon, Apr 24, 2023, 12:30 pm1:30 pm

The actomyosin cytoskeleton is a naturally occurring active gel found in virtually all mammalian cells. Its ability to contract allows cells to move, change shape, exert force, sense stiffness, and maintain constant tension. In order for the “hardware” of actomyosin gels to support such a diverse set of mechanical tasks, it is tightly coupled…

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Biophysics Seminar: Heather Lynch, Stony Brook University| Emergent pattern formation in penguin colonies: Life at the crossroads of ecology, geology, computational geometry, and computer vision
Mon, Feb 20, 2023, 12:30 pm1:30 pm

Aggregations are common in biological systems at a range of scales and may be driven by exogenous constraints such as environmental heterogeneity and resource availability or by “self-organizing” interactions among individuals. One mechanism leading to self-organized animal aggregations is captured by Hamilton’s “selfish herd” hypothesis, which…

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Biophysics Seminar Series
Mon, Feb 20, 2023, 12:30 pm1:30 pm

Aggregations are common in biological systems at a range of scales and may be driven by exogenous constraints such as environmental heterogeneity and resource availability or by “self-organizing” interactions among individuals. One mechanism leading to self-organized animal aggregations is captured by Hamilton’s “selfish herd” hypothesis, which…

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A free lecture open to the public.
CPBF Seminar Series
Mon, Feb 13, 2023, 12:30 pm1:30 pm

Super-resolution optical microscopy has become a powerful tool to study the nanoscale spatial distribution of molecules of interest in biological cells, tissues and other structures over the last years. Imaging these distributions in the context of other molecules or the general structural context is, however, still challenging. I will present…

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Biophysics Seminar: Na Ji, UC Berkeley| Imaging the brain at high spatiotemporal resolution
Mon, Dec 12, 2022, 12:30 pm1:30 pm

To understand computation in the brain, one needs to understand the input-output relationships for neural circuits and the anatomical and functional properties of individual neurons therein. Optical microscopy has emerged as an ideal tool in this quest, as it is capable of recording the activity of…

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A free lecture open to the public.
Biophysics Seminar: Brad Dickerson, Princeton University| TBA
Mon, Dec 5, 2022, 12:30 pm1:30 pm
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A free lecture open to the public.
Biophysics Seminar: Mustafa Mir, CHOP| Quantifying transcriptional regulation across multiple-scales in developing embryos
Mon, Nov 28, 2022, 12:30 pm1:30 pm
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Biophysics Seminar: Tian-Ming Fu, Princeton University| Probing Biological Dynamics in Multicellular Organisms: from long-term electrophysiology to high-resolution imaging
Mon, Nov 21, 2022, 12:30 pm1:30 pm

The urgency to probe biological dynamics is impeded by a major challenge: the large dynamic range of biological processes—interactions of molecules within milliseconds can lead to changes across the whole-organism over days to years. It calls for measurements with both high spatiotemporal resolution and large-scale long-term coverage. However,…

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Biophysics Seminar: Anders Hansen, MIT| Dynamics of 3D Genome Structure and Function
Mon, Nov 14, 2022, 12:30 pm1:30 pm

Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop extruding cohesins. These loops and domains are thought to play critical roles in regulating gene expression by regulating long-range enhancer-promoter interactions. But whether CTCF/cohesin loops are stable or dynamic structures was…

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Biophysics Seminar: Kandice Tanner, NIH| Microenvironment regulation of metastasis
Mon, Nov 7, 2022, 12:30 pm1:30 pm

In the event of metastatic disease, emergence of a lesion can occur at varying intervals from diagnosis and in some cases following successful treatment of the primary tumor.  Genetic factors that drive metastatic progression have been identified, such as those involved in cell adhesion, signaling, extravasation and metabolism. However,…

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A free lecture open to the public.
Canceled: Biophysics Seminar: Roseanna Zia, Stanford University| How Colloidal Physics Instantiate Life in Biological Cells
Mon, Oct 31, 2022, 12:30 pm1:30 pm

We are interested in how physics at the colloidal scale instantiate life in biological cells. While principles from physics have driven recent paradigm shifts in how collective biomolecular behaviors orchestrate life, many mechanistic aspects of e.g. transcription, translation, and condensation remain mysterious because…

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Biophysics Seminar: Marc Gershow, NYU| Maggots! Making Memories and Reading Minds
Mon, Oct 10, 2022, 12:30 pm1:30 pm

My lab studies the brains of larval fruit flies as models of neural computation. We are interested in the rules by which the larval brain transforms sensory input into motor output to navigate an uncertain environment, how the larva’s brain changes these rules as it learns new information, and how these rules and changes are encoded in the…

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Biophysics Seminar: Stephen Floor, UCSF| On measurement in RNA biology
Mon, Sep 26, 2022, 12:30 pm1:30 pm

Measurement of natural systems typically involves perturbation and interpretation. In this talk, I will discuss the implications of measurement in the context of RNA in gene expression in human cells. I will focus on measurements of RNA biology using high-throughput sequencing, which are powerful for their scale but also involve perturbations…

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A free lecture open to the public.
Biophysics Seminar: Shenshen Wang, UCLA| Limit and potential of immune learning against changing targets
Mon, Sep 19, 2022, 12:30 pm1:30 pm
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Biophysics seminar: Marc Gershow, New York University| TBD
Mon, May 2, 2022, 12:30 pm12:30 pm
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A free lecture open to the public.
Biophysics Seminar: Arseny Finkelstein, Tel-Aviv University| TBA
Sun, May 1, 2022, 12:30 pm1:30 pm
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Biophysics seminar: Andrea Liu, University of Pennsylvania| How Materials Can Learn
Mon, Apr 25, 2022, 12:30 pm12:30 pm

How does learning occur? Neural networks learn via optimization, where a loss function is minimized by a computer to achieve the desired result. But physical networks such as mechanical spring networks or flow networks have no central processor so they cannot minimize such a loss function. An alternative is to encode local rules into those…

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A free lecture open to the public.