Gene expression in all organisms is controlled by short DNA and RNA sequences called cis-regulatory elements (CREs). Proteins in the cellular milieu bind to nucleic acid sequences present within CREs, interact with one another, and thus form macromolecular complexes that modulate the expression of nearby genes.
Audience: A free lecture open to the public.
Cold Spring Harbor Laboratory
Massively parallel assays, machine learning, and the biophysics of gene regulation
The study of small experimental communities has been key to the development of ecology as a discipline. Yet, for most ecological communities, the number of experiments required to build, model, or analyze the system vastly exceeds what is feasible, rendering these communities experimentally intractable.
The advent of the Gaia era has led to potentially revolutionary understanding of dark matter dynamics in our galaxy, which has important consequences for direct detection experiments. In this talk, I will discuss the effects of various dark matter substructures inferred from the Gaia data on possible direct detection signals at next-generation...
Observations of the cosmic microwave background form the pillar of our current understanding of cosmology. Measurements of the temperature and polarization anisotropies of the CMB extending to small angular scales set tight constraints on cosmological parameters, probing both the standard LCDM model and the physics of inflation.
A useful guiding principle for the search of topological superconductors is to relate the topological invariants with the behavior of the pairing order parameter on the normal-state Fermi surfaces. In this talk, we will discuss how this paradigm can be integrated with the notion of symmetry indicators, which enables an efficient diagnosis of...